Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1996-06-06
1998-12-01
Achutamurthy, Ponnathapura
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
530300, 530811, A61K 4900, A61K 3800
Patent
active
058434054
ABSTRACT:
The invention relates to peptides or fragments thereof which are immunochemically reactive with Epstein-Barr Virus (EBV) antibodies. New antibodies directed to said peptides or fragments thereof are also part of the invention.
The invention also relates to a method for the detection of EBV or antibodies directed against EBV in a test fluid and also to an immunochemical reagent comprising a peptide, a fragment or a polypeptide according to the invention and a test kit to be used when applying the said detection methods.
Detection of EBV in a test fluid or tissue specimen using antibodies, monoclonal and polyclonal, directed to the said peptide, which have the characteristics of detecting both native and denatured EBV-EA protein is also part of said invention.
REFERENCES:
patent: 4761470 (1988-08-01), Emini
patent: 4879213 (1989-11-01), Fox et al.
patent: 5087557 (1992-02-01), McClure
patent: 5256768 (1993-10-01), Milman
R.I. Fox et al., Journal of Clinical Laboratory Analysis, 1:1:140-145, 1987 .
Achutamurthy Ponnathapura
Akzo Nobel N.V.
Gormley Mary E.
Klesner Sharon N.
Park Hankyel T.
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