Epsilon immunoglobulin chain derived peptides for induction...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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C435S007100, C435S007500, C435S007940, C435S069300, C435S070210, C435S452000, C435S975000, C436S513000, C436S518000, C436S547000, C436S548000, C530S387900, C530S388250, C530S389300, C530S391300

Reexamination Certificate

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10052788

ABSTRACT:
The present invention relates to identification of polypeptides useful for generating antibodies specific for non-human IgE, particularly equine IgE. The invention, therefore, also relates to antibodies that specifically bind to IgE and methods to detect IgE using the antibodies. The invention also provides a kit for detection of IgE.

REFERENCES:
patent: 5583005 (1996-12-01), Nishimura et al.
patent: 5629415 (1997-05-01), Hollis et al.
patent: 0044710 (1982-01-01), None
Halliwell and Hines, “Studies on equine recurrent uveitis. I: Levels of immunoglobulin and albumin in the aqueous humor of horses with and without intraocular disease”,Current Eye Research, 4:1023-1031 (1985).
Marti, E. et al., “Partial sequence of the equine immunoglobulin epsilon heavy chain cDNA”Journal of Veterinary Immunology and Immunopathology, 47:363-367 (1995).
Marti, E. et al., “Chicken antibodies to a recombinant fragment of the equine immunoglobulin epsilon heavy-chain recognising native horse IgE,”Veterinary Immunology and Immunopathology, 59:253-270 (1997).
Navarro, P. et al., “The Complete cDNA and Deduced Amino Acid Sequence of Equine IgE,”Journal of Molecular Immunology, 32:1-8 (1995).
Watson, J.L. et al., “Isolation and Partial Expresion of a cDNA Clone Encoding Equine IgE Heavy Chain and Production of Polyclonal Antibodies to the Recombinant Protein,”Veterinary Allergy and Clinical Immunology, 5:135-142 (1997).
Watson, J.L. et al., “Phenotypic Characterization of Lymphocyte Subpopulations in Horses Affected with Chronic Obstructive Pulmonary Disease and in Normal Controls,”Vet. Pathol.34:108-116 (1997).
Griot-Wenk, M.E. et al., “Partial sequences of feline and caprine immunoglobulin epsilon heavy chain cDNA and comparative binding studies of recombinant IgE fragment-specific antibodies across different species,”Journal of Veterinary Immunology and Immunopathology, 75:59-69 (2000).

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