Epoxidation of lower .alpha.-olefins

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435177, 435249, 435250, 435822, 435858, C12P 1702, C12N 1102, C12N 128, C12N 130

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043682677

ABSTRACT:
A process is disclosed for the epoxidation of lower .alpha.-olefins dienes or vinyl aromatic compounds by contacting said compounds, under aerobic conditions in the presence of microorganisms, genetically engineered organisms thereof or enzyme preparations derived from said microorganisms. The microorganisms, genetically engineered organisms, or enzyme preparations derived therefrom are preferably those microorganisms which are known as methylotrophs particularly those which have previously grown under aerobic conditions in a nutrient medium containing methane.

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Cerniglia et al., "Microbial Oxidation & Assimilation of Propylene" Applied & Environmental Microbiology, Dec. 1976, pp. 764-768.
Nesterov "Activity of CH.sub.4 Oxidizing Bacteria in the Absorbed State" Chemical Abstracts, vol. 84, No. 5 (1976) Abstract No. 27940c.
Colby et al., "Soluble CH.sub.4 Mono-Oxygenase of Methylococcus Capsulatus" Biochem. J., vol. 165 (1977), pp. 395-402.
van der Linden et al., "Induction of Alkane Oxidizing & .alpha.-Olefin Epoxidizing Enzymes by a Nonhydrocarbon in a Pseudomonas" Chem. Abst., vol. 67 (1967), Abst. No. 106124s.

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