Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing
Reexamination Certificate
2005-02-08
2005-02-08
Tate, Christopher R. (Department: 1654)
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
C424S776000, C435S123000, C435S180000
Reexamination Certificate
active
06852315
ABSTRACT:
A method has been discovered for the epoxidation of a compound having at least one carbon-carbon double bond, the method involves reacting a compound having at least one carbon-carbon double bond, a solvent, an oxidant, and membrane bound peroxygenase. Also discovered is a method for preparing the membrane bound peroxygenase involving grinding seeds containing peroxygenase to produce ground seeds, homogenizing the ground seeds in a buffer to form a slurry, centrifuging the slurry to produce a first supernatant, centrifuging the first supernatant to produce a second supernatant, and filtering said second supernatant through a protein-binding membrane filter to produce membrane bound peroxygenase; optionally the second supernatant is filtered through a hydrophilic membrane filter prior to filtering the second supernatant through a protein-binding membrane filter.
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Foglia Thomas A.
Nunez Alberto
Piazza George J.
Fado John D.
Stover G. Byron
Tate Christopher R.
The United States of America as represented by the Secretary of
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