Epothilone derivatives and methods for making and using the...

Details Epothilone derivatives and methods for making and using the... Epothilone derivatives and methods for making and using the...

2005-05-17

2005-05-17

Prats, Francisco (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S252100, C435S118000, C435S120000

Reexamination Certificate

active

06893859

ABSTRACT:
This invention relates to compounds of formula (I)and to pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, W, X, Y, and Ar are as defined herein. Compounds of formula (I) are useful in the treatment of diseases or conditions characterized by cellular hyperproliferation. This invention also relates to means for the preparation of compounds of formula (I); formulations containing compounds of formula (I); and methods for the use of said compounds and formulations in the treatment of a disease or condition characterized by cellular hyperproliferation, including cancer.

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