Epitopic regions of pneumococcal surface protein A

Details Epitopic regions of pneumococcal surface protein A Epitopic regions of pneumococcal surface protein A

1995-06-06

1997-10-21

Caputa, Anthony C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

530324, 530350, 530825, 4241901, 42419711, 4242001, 4242441, 4352523, C07K 14315, A61K 3909, A61K 3816

Patent

active

056797680

ABSTRACT:
A region of the PspA protein of the Rx1 strain of Streptococus pneumoniae has been identified as containing protection-eliciting epitopes which are cross-reactive with PspAs of other S.pneumoniae strains. The region comprises the 68-amino acid sequence extending from amino acid residues 192 to 260 of the Rx1 PspA strain.

REFERENCES:
Waltman et al, "Variation in the molecular weight of PspA(pneumococcal surface protein A) among Streptococcus pneumoniae", Microbial Pathogenesis 1990; 8:61-69.
Waltman et al, Microbial Pathogenesis 1988, vol. 5: pp. 159-167.
Cohen et al, Science 1994, 263:488-489.
Engel et al, EMBO 1992,11:4369-4378.
Cohen et al, 1990, Proteins 7:1-15.
Fishetti et al, 1990, Molec. Micro. 4:1603-1605.
Young and Davis PNAS 80: 1194-1198 Mar. 1983.
"Antibodies, A Laboratory Manual", E. Harlow et al (Ed) See Chapter 13 pp. 514-551.
Pongor et al. Methods in Enzymology 154:450-473. 1987.
McDaniel et al (I), J.Exp.Med. 160:386-397, 1984.
McDaniel et al (II), Microbial Pathogenesis 1:519-531, 1986.
McDaniel et al (III), J.Exp.Med. 165:381-394, 1987.
McDaniel et al (IV), Infect. Immun., 59:222-228, 1991.
Crain et al, Infect. Immun., 58:3293-3299, 1990.
Abstracts of 89th Annual Meeting of the American Society for Microbiology, P.125, item D-257, May 1989.
Abstracts of 90th Annual Meeting of the American Society for Microbiology, p. 98, item D-106, May 1990.
Abstracts of 3rd International ASM Conference on Streptococcal Genetics, p.11, item 12, Jun. 1990.
Talkington et al, Infect. Immun. 59:1285-1289, 1991.
Yother et al, J. Bacteriol. 174:601-609, 1992.
Yother et al, J. Bacteriol. 174:610-618, 1992.
McDaniel et al (V), Microbiol Pathogenesis, 13:261-268; 1992.
Stover et al. "New use of BCG for recombinant vaccines" Nature (351)456-460, Jun. 1991.

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