Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1995-06-06
1999-12-07
Housel, James C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
4242371, 530350, 435 691, 4353201, A61K 3909
Patent
active
059978821
ABSTRACT:
Regions of the PspA protein of the R.times.1 strain of Streptococcus pneumoniae have been identified as containing protection-eliciting epitopes which are cross-reactive with PspAs of other S. pneumoniae strains and which is cross-protective. One region comprises the 68-amino acid sequence extending from amino acid residues 192 to 260 of the R.times.1 PspA strain while another region comprises the C-terminal amino acid sequence extending from amino acid residues 293 to 588 of the R.times.1 PspA strain.
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Briles David E.
McDaniel Larry S.
Yother Janet L.
Frommer William S.
Graser Jennifer
Housel James C.
Kowalski Thomas J.
UAB Research Foundation
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