Epitopic regions of pneumococcal surface protein a

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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4242371, 530350, 435 691, 4353201, A61K 3909

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059651415

ABSTRACT:
A region of the PspA protein of the Rx1 strain of Streptococcus pneumoniae has been identified as containing protection-eliciting epitopes which are cross-reactive with PspAs of other S. pneumoniae strains and which is cross-protective. The region comprises the 68-amino acid sequence extending from amino acid residues 192 to 260 of the Rx1 PspA strain.

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