Epitopes formed by non-covalent association of conjugates

Details Epitopes formed by non-covalent association of conjugates Epitopes formed by non-covalent association of conjugates

2000-06-27

2008-08-19

Shibuya, Mark L. (Department: 1639)

Combinatorial chemistry technology: method, library, apparatus

Library, per se

Library containing only organic compounds

C435S007100, C506S013000, C506S015000

Reexamination Certificate

active

07413538

ABSTRACT:
A composition for interacting with a ligand, which composition comprises a non-covalent association of a plurality of distinct conjugates, each conjugate comprising a head group and a tail group, wherein the tail groups of the conjugates form a hydrophobic aggregation and the conjugates are movable within the association so that, in the presence of a ligand, at least two of the head groups are appropriately positioned to form an epitope capable of interacting with the ligand more strongly than each of head groups individually.

REFERENCES:
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patent: 6217886 (2001-04-01), Onyuksel et al.
patent: 2003/0095962 (2003-05-01), Ueda et al.
patent: WO 95/02684 (1995-01-01), None
patent: WO 96/23881 (1996-08-01), None

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