Epipodophyllotoxin glycosides

Details Epipodophyllotoxin glycosides Epipodophyllotoxin glycosides

1990-06-11

1991-03-05

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 35, 536 171, 536 181, 536 182, A61K 3170, C07H 1104, C07H 1500

Patent

active

049979310

ABSTRACT:
The present invention relates to novel antitumor compounds which are 4'-demethylepipodophylloxtoxin derivatives. More particularly, the novel compounds are 4'-demethylepipodophyllotoxin allopyranosides, allofuranosides, and mannopyranosides.

REFERENCES:
patent: 3524844 (1970-08-01), Keller-Juslen et al.
patent: 4904768 (1990-02-01), Saulnier et al.
J Med. Chem., 1971, 14:936-940.
Chem. Lett., 1987, 799-802.
Watanabe et al., Carb. Res. 154:165-176 (1986).

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