Epimeric azahomoerythromycin A derivative, intermediates and met

Details Epimeric azahomoerythromycin A derivative, intermediates and met Epimeric azahomoerythromycin A derivative, intermediates and met

1984-04-17

1985-07-02

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, 536 74, A61K 3171, C07H 1708

Patent

active

045268894

ABSTRACT:
Antibacterial 4"-epi-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A, pharmaceutically-acceptable salts thereof, pharmaceutical compositions comprising antibacterially-effective amounts thereof, a method of treatment of bacterial infections with antibacterially effective amounts thereof, and intermediates for the synthesis thereof from erythromycin A.

REFERENCES:
patent: 3478014 (1969-11-01), Djokic et al.
patent: 3574185 (1971-04-01), Tamburasev et al.
patent: 3660376 (1972-05-01), Massey
patent: 3674773 (1972-07-01), Kurath
patent: 3681326 (1972-08-01), Von Esch
patent: 4316010 (1982-02-01), Nagel
patent: 4328334 (1982-05-01), Kobrehel et al.
patent: 4349545 (1982-09-01), d'Ambrieres et al.
patent: 4382085 (1983-05-01), Sciavolino et al.
BNA's "Patent, Trademark & Copyright Journal", vol. 29, 11/84.
Lullmann et al., "CRC Critical Reviews in Toxicology", 11/75, pp. 185-218.
Massey et al., Tetrahedron Letters, pp. 157-160, 1970.

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