Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and it

Details Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and it Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and it

1997-10-16

1999-05-04

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Digestive system regulator containing solid synthetic...

424451, 424464, 5147723, A61K 3174, A61K 948, A61K 920, A61K 4730

Patent

active

059002336

ABSTRACT:
An anion-binding hydrophilic epichlorohydrin and 1-(3-aminopropyl)imidazole copolymeric bile acid sequestrant, pharmaceutical compositions thereof, and use thereof in the treatment of ailments or conditions in which a bile acid sequestrant and inhibitor of fat absorption is indicated.

REFERENCES:
patent: 4557930 (1985-12-01), Kihara et al.
patent: 4777042 (1988-10-01), Toda et al.
patent: 5380522 (1995-01-01), Day
patent: 5624963 (1997-04-01), Mandeville, III et al.
Revici, Chemical Abstracts, vol. 108, #68958, 1988.
Nomura et al., Chemical Abstract , vol. 114, #30,145, 1991.
(Mit) Kihara et al., Chemical Abstracts, vol. 97, #203,236, 1983.
Katogi et al., Chemical Abstracts, vol. 127, #239,147, 1997.
Toepfl, Chemical Abstracts, vol. 106, #51 645 1987.
Hashim, S.A., et al., "Experimental steatorrhea induced in man by bile acid sequestrant.", Proc. Soc. Exp. Biol. Med. 106: 173-175 (1965).
Bierman EL, "Atherosclerosis and Other Forms of Arteriosclerosis." In: Harrison's Principles of Internal Medicine, 13th ed., KJ Isselbacher et al. (eds.). New York, McGraw-Hill, pp. 1106-1116 (1994).
Toda H. et al., "Bile acid binding and hypocholesteremic activity of a new anion exchange resin from 2-methylimidazol and epichlorohydrin", J. Pharm. Sci. 77:531-533 (1988).
Benson G.M. et al. "SK&F 97426-A; a novel bile acid sequestrant wih higher affinities and slower dissociation rates in vitro than cholestyramine"; J Pharm Sci. 86:76-81 (1997).
American Gastroenterological Association Medical Position Statement: Irritable Bowel Syndrome. Gastroenterology 112:2118-2119 (1997).
Drossman DA, Whitehead WE, Camilleri M., "Irritable bowel syndrome: a technical review for practice guideline development", Gastroenterology 112:2120-2137 (1997).
Snape WJ Jr., "Irritable bowel syndrome", In: Bockus Gastroenterology, 5th edition (W.S. Haubrich, F. Schoffner, ed.) Philadelphia: W.B. Saunders, pp. 1619-1636 (1995).
Harrison's Principles of Internal Medicine, 13th ed., K.J. Isselbacher et al. (eds). New York, McGraw-Hill, pp. 446 ff (1994).
Williams' Endocrinology, 8th ed., J.D. Wilson, D.W. Foster (eds). Philadelphia, Saunders, pp. 1335 ff. (1992).
Goodman & Gilman's, The Pharmacological Basis of Therapeutics, 9th ed., J.G. Hardman et al. (eds). New York, McGraw-Hill, pp. 875 ff (1996).

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