Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-05-23
1995-10-31
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514413, 548466, 5483121, A61K 3140, C07D40304
Patent
active
054629560
ABSTRACT:
The present invention is directed to compounds, compositions and methods of treating pain, and derivatives that have potent analgetic activity. The compounds have the formula: ##STR1## wherein R.sup.1 is selected from H, lower alkyl, C.sub.3 -C.sub.9 cycloalkyl, acyl, C.sub.3 -C.sub.9 cycloalkylalkyl, haloalkyl, alkenyl, alkynyl, hydroxyalkyl, C.sub.3 -C.sub.8 cycloalkenyl C.sub.3 -C.sub.8 cycloalkynyl and phenyl; and wherein R is selected from cycloalkyl, aryl, heteroaryls (selected from the group consisting of pyridyl, thienyl, furanyl, imidazolyl, pyrazinyl, and pyrimidyl) or phenoxy and wherein said R groups can be substituted with hydroxyl, C.sub.1 -C.sub.6 lower alkyl, C.sub.2 -C.sub.6 alkenyl, C.sub.1 -C.sub.6 lower alkoxyl, halo, C.sub.1 -C.sub.6 haloalkyl, amino, C.sub.1 -C.sub.6 alkylamino and C.sub.2 -C.sub.10 dialkylamino, and sulfonamido or a pharmaceutically acceptable salt thereof.
REFERENCES:
patent: 4499099 (1985-02-01), Watts
patent: 5015655 (1991-05-01), Galliani et al.
Daly John W.
Garraffo Hugo M.
Spande Thomas F.
Fan Jane
The United States of America as represented by the Department of
LandOfFree
Epibatidine and derivatives, compositions and methods of treatin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Epibatidine and derivatives, compositions and methods of treatin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Epibatidine and derivatives, compositions and methods of treatin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1772663