EphA4-positive human adult pancreatic endocrine progenitor...

Details EphA4-positive human adult pancreatic endocrine progenitor... EphA4-positive human adult pancreatic endocrine progenitor...

2005-09-27

2010-10-05

Kim, Taeyoon (Department: 1651)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S041000, C435S070100, C435S370000, C435S374000, C424S093700

Reexamination Certificate

active

07807459

ABSTRACT:
The invention relates to the discovery of a selective cell surface marker that permits the selection of a unique subset of pancreatic stem cells having a high propensity to differentiate into insulin-producing cells or into insulin-producing cell aggregates.

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Langley et al. 1989. Expression of the neural cell adhesion molecule NCAM in endocrine cells. J. Histochem. Cytochem. 37(6):781-791.
Tezel et al. 2001. Expression of Neural Cell Adhesion Molecule in Pancreatic Cancer. Pancreas. vol. 22:122-125.
Nakamura et al. 2004. Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection. Oncogene. 23:2385-2400.
Fujisawa et al. 2003. CD56-positive Cells with or without Synaptophysin Expression are Recognized in the Pancreatic Duct Epithelium: A S tudy with Adult and Fetal Tissues and Specimens from Chronic Pancreatitis. Acta Med. Okayama, vol. 57, No. 6, pp. 279-284.

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