Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2008-07-22
2008-07-22
Ulm, John (Department: 1649)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C435S069100, C530S326000, C536S023500
Reexamination Certificate
active
11387009
ABSTRACT:
The present invention provides assays for the study of the interaction of EPF and its EPF-related peptides with a hDRR receptor. The assays are useful to identify whether a test compound can bind to the hDRR receptor under conditions in which EPF or related peptide can bind to the receptor. The assays are also useful to determine whether the test compound is an agonist or antagonist of hDRRs. The above assays can be performed in a variety of formats including competitive, non-competitive and comparative assays in which the interaction of EPF or EPF-related peptides with hDRRs is assessed as a positive or negative control or compared to the results obtained with the test compound.
REFERENCES:
patent: WO 95/15339 (1995-06-01), None
patent: WO 97/18309 (1997-05-01), None
patent: WO 99/32519 (1999-07-01), None
patent: WO 01/36471 (2001-05-01), None
patent: WO 01/19983 (2003-03-01), None
Lembo et al., Proenkephalin A Gene Products Activate a New Family of Sensory Neuron-Specific GPCRs, Mar. 2002, Nature neuroscience 5(3):201-209.
Morton et al., Production of a Recombinant Form of Early Pregnancy Factor That Can Prolong Allogeneic Skin GraftSurvival Time in Rats, 2000, Immunology and Cell Biology 78:603-607.
Database EMBL Online “Heat Shock Protein 10 (Cpn10, groES)”,Database accession No. 042283.
Jarvis, Jackie A. et al., “Solution Structure of the Acetylated and Noncleavable Mitochondrial Targeting Signal of Rat Chaperonin 10”,J. Biol. Chem., 270:1323-1331 (1995).
Database EMBL 1998, “ok82f05.s1 NCI—CGAP—Kid3Homo sapienscDNA clone Image: 1520481 3′ similar to SW:CH10—Human Q04984 10 KD Heat Shock Protein, Mitochondrial;, mRNA sequence”, Database accession No. AA923068.
Maria J. Somodevilla-Torres et al., “Preparation and characterization of polyclonal antibodies against human chaperonin 10”, Cell Stress & Chaperones (2000)5, (1), pp. 14-20.
Bender Eckhard
Buist Arjan
Clynen Elke J. H.
Meeusen Tom J. L.
Schoofs Liliane A. H.
Janssen Pharmaceutica N.V.
Ulm John
Woodcock & Washburn LLP
LandOfFree
EPF derived peptides and therapeutic compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with EPF derived peptides and therapeutic compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and EPF derived peptides and therapeutic compositions will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3942577