Enzymic oxidation of fatty acids on a porous bed solid support

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435182, 435189, C12P 764, C12N 1104, C12N 902

Patent

active

051852527

ABSTRACT:
A process for enzymic oxidation of a fatty acid to produce an oxidation product and an apparatus for carrying out the process are presented. The process is carried out in the presence of water and oxygen wherein the fatty acid, water and enzyme for the oxidation are substantially uniformly distributed throughout a porous bed of solid suppport material in the substantial absence of a continuous liquid phase. Oxygen is passed through the bed and the oxidation product is recovered from the porous bed. By this process, methyl ketones can be produced from saturated fatty acids. The porous bed is contained within an apparatus which includes a sealable vessel, a gas inlet for supplying the oxygen gas to the reactor and a gas outlet. The gas is forced through the inlet and into passage means defining a plurality of upwardly extending passages that can open along their length into the bed and that are spaced 5 to 20 cm apart.

REFERENCES:
patent: 4029546 (1977-06-01), Brouillard
patent: 4033820 (1977-07-01), Brouillard
patent: 4212949 (1980-07-01), Kozkemyakin et al.
patent: 4451566 (1984-05-01), Spencer

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