Enzymes for the production of 2-keto-L-gulonic acid

Details Enzymes for the production of 2-keto-L-gulonic acid Enzymes for the production of 2-keto-L-gulonic acid

2007-08-14

2007-08-14

Achutamurthy, P. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C435S440000, C435S004000, C435S006120, C435S025000, C435S252300, C435S320100, C435S069100, C435S071100, C536S023200, C536S023700

Reexamination Certificate

active

09332886

ABSTRACT:
Mutants of 2,5-diketo-D-gluconic acid reductase A, an enzyme used to produce 2-keto-L-gulonic acid, a precursor of ascorbic acid (vitamin C) are prepared by site-directed mutagenesis. These mutants have increased catalytic activity, increased expression levels, and/or enhanced temperature stability.

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