Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1992-09-08
1994-12-27
Low, Christopher S. F.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
435189, 435 691, 536 232, 930240, C12N 904
Patent
active
053765443
ABSTRACT:
Mutants of 2,5-diketo-D-gluconic acid reductase A, an enzyme used to produce 2-keto-L-gulonic acid, a precursor of ascorbic acid (vitamin C) are prepared by site-directed mutagenesis. These mutants have increased catalytic activity, increased expression levels, and/or enhanced temperature stability.
REFERENCES:
patent: 5008193 (1991-04-01), Anderson et al.
Anderson et al. 1985, Science 230, 144-149.
Rastetter, W. H. 1983, Trends Biotechnol. 1, 80-84.
Sonoyama, et al. 1987, J. Ferment. Technol. 65,311-317.
Imanaka et al. 1986, Nature 324, 695-697.
Grindley et al. 1988, Appl. Environ. Microbiol. 54, 1770-1775.
Anderson Stephen
Hurle Mark
Lazarus Robert A.
Powers David B.
Low Christopher S. F.
Pepper Frederick W.
Rutgers The State University of New Jersey
LandOfFree
Enzymes for the production of 2-keto-L-gulonic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Enzymes for the production of 2-keto-L-gulonic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enzymes for the production of 2-keto-L-gulonic acid will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-918745