Enzyme treatment of foodstuffs for Celiac Sprue

Details Enzyme treatment of foodstuffs for Celiac Sprue Enzyme treatment of foodstuffs for Celiac Sprue

2008-01-22

2008-01-22

Tsang, Cecilia J. (Department: 1654)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C530S374000, C514S002600

Reexamination Certificate

active

10969314

ABSTRACT:
Administering an effective dose of glutenase to a Celiac or dermatitis herpetiformis patient reduces levels of toxic gluten oligopeptides, thereby attenuating or eliminating the damaging effects of gluten.

REFERENCES:
patent: 4203967 (1980-05-01), Gallo-Torres
patent: 5834428 (1998-11-01), Drucker
patent: 6197356 (2001-03-01), Girsh
patent: 6319726 (2001-11-01), Schuppan
patent: 6410550 (2002-06-01), Coe et al.
patent: 2001/0007690 (2001-07-01), Girsh
patent: 2001/0036639 (2001-11-01), Fine
patent: 2002/0039599 (2002-04-01), Lin et al.
patent: 2003/0215438 (2003-11-01), Hausch
patent: 2004/0241664 (2004-12-01), Dekker et al.
patent: 0 905 518 (1999-03-01), None
patent: WO94/26774 (1994-11-01), None
patent: WO 01/25793 (2001-04-01), None
patent: WO 03/068170 (2003-08-01), None
Lion. Flavobacterium meningosepticum. Genbank Accession #EMBL #: D10980. Aug. 1, 1992. http://www.infobiogen.fr/srs71bin/cgi-bin/wgetz?-id+4jqa61Mc9PO+[uniprot-ID:PPCE—Flame]+-e.
Online-Medical Dictionary. “Amino acid”. http://cancerweb.ncl.ac.uk/cgi-bin/omd?query=amino+acid. Nov. 13, 1997.
Ahnen et al., Intestinal Aminooligopeptidase. In Vivo Synthesis on Intracellular Membranes of Rat Jejunum, 1982, J. Biol. Chem., 257, 12129-35.
Arentz-Hansen et al., the Intestinal T Cell Response toα—Gliadin in Adult Celiac Disease is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase, 2000, J. Exp. Med., 191, 603-12.
Bordusa et al., The Specificity of Prolyl Endopeptidase from Flavobacterium Meningoseptum: Mapping the S′ Subsites by Positional Scanning Via Acyl Transfer, 1998, Bioorg. Med. Chem., 6, 1775-80.
Colot et al., The Genes Encoding Wheat Storage Proteins: Towards a Molecular Understanding of Bread-Making Quality and its Genetic Manipulation, 1990, Genet Eng., 12:225-41.
Database Derwent, Acc-No. 1996-329479. HLA-Binding Oligopeptide and an Immuno: Regulator Contgit—Used in the Treatment of Auto: Immune Disease, 1999.
Lahteenoja et al., Local Challenge on Oral Mucosa with an Alpha-Gliadin Related Synthetic Peptide in Patients with Celiac Disease, 2000, Am. J. Gastroenterol., 95: 2880.
Schuppan, Current Concepts of Celiac Disease Pathogenesis, 2000, Gastroenterology, 119, 234-42.
Wieser, the Precipitating Factor in Coeliac Disease, 1995, Baillieres Clin Gastroenterol, 9(2):191-207.
Wieser, 1996, Relation Between Structure an Dcoeliac Toxicity, Acta Paediatr Suppl., 412:3-9.
Yoshimoto et al., Prolyl Endopeptidase from Flavobacterium Meningosepticum: Cloning and Sequencing of the Enzyme Gene, 1991, J. Biochem., 110, 873-8.
Frazer et al., Gluten—Induced Enteropathy the Effect of Partially Digested Gluten, The Lancet, 1959 p. 252-255.
Messer et al., Oral Papain in Gluten Intolerance, The Lancet, 1976, p. 1022.
Messer et al., Studies on the mechanism of destruction of the toxic action of wheat gluten in celiac disease by crude papain, Gut, 1964, 5: 295-303.
Moodie, Peter, Traditional Baking Enzymes-Proteases, Enzyme Development Corporation.

Affiliated with

Also associated with

Rating

Enzyme treatment of foodstuffs for Celiac Sprue does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enzyme treatment of foodstuffs for Celiac Sprue, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enzyme treatment of foodstuffs for Celiac Sprue will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3907787