Enzyme-treated hesperidin, process for producing the same and me

Details Enzyme-treated hesperidin, process for producing the same and me Enzyme-treated hesperidin, process for producing the same and me

1997-06-24

1999-03-23

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

A61K 3170

Patent

active

058859691

ABSTRACT:
An enzyme-treated hesperidin, comprising alpha-glucosyl hesperidin, hesperidin and beta-monoglucosyl hesperetin, wherein the content of hesperidin is 0.1 part or less by weight; and that of beta-monoglucosyl hesperetin, 0.1 to 0.5 part by weight, on the basis of 1 part by weight of alpha-glucosyl hesperidin. The present invention also provides a process to produce enzyme-treated hesperidin, which comprises subjecting a solution containing alpha-glucosyl hesperidin and intact hesperidin to alpha-L-rhamnosidase to convert the intact hesperidin into beta-monoglucosyl hesperetin. The enzyme-treated hesperidin, which is excellent in water solubility and is free from crystal precipitation (clouding) even if stored for a prolonged period of time, can be produced from a material containing alpha-glucosylhesperidin and hesperidin by conducting the above simple treatment of material. The present invention further provides a method of using the enzyme-treated hesperidin. The enzyme-treated hesperidin can be used in the prevention of clouding of a canned tangerine and prevention of fading of natural coloring matter.

REFERENCES:
patent: 3583894 (1971-06-01), Horowitz et al.
patent: 4332825 (1982-06-01), Miyawaki et al.
patent: 5077206 (1991-12-01), Cheetham et al.
patent: 5641659 (1997-06-01), Meiwes et al.
patent: 5652124 (1997-07-01), Hijiya et al.
Database WPI Section Ch, Week 9622, Derwent Publications Ltd., London, Great Britain: (1996) AN 96-216143, XP002065322 & Japanese Patent Laid Open No. JP 08 080 177 Abstract, Sep. 12, 1992, 1 page, English language.
Japanese Patent Abstract No. 3-7593, Jan. 14, 1991, 2 pages, (English language), 1 page (Japanese language).
Japanese Patent Abstract No. 8080177, Mar. 26, 1996, 1 page, (English language, 1 page (Japanese language).

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