Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Patent
1997-12-03
2000-11-07
Redding, David A.
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
4352931, 4352971, 4352991, C12M 300
Patent
active
061435562
ABSTRACT:
The invention provides a process for gas separation wherein a selected gas in a mixed gas stream is contacted by an enzyme having an active site directly contacted by the mixed gas stream, and the selected gas is at least partially removed from the mixed gas stream. In one embodiment a selected gas in a gas phase is contacted by a solvated enzyme wherein the enzyme active site is in direct contact with the gas phase, and the selected gas is converted to a first product in a condensed phase by contact with the solvated enzyme. The invention also provides a bioreactor which comprises a vessel having at least one first wall enclosing an inlet zone, and at least one second wall enclosing a second phase zone, a portion of the second wall is permeable to at least one selected gas in the inlet zone, and retains the second phase in the second phase zone; a portion of the second wall also comprises a support surface with at least one enzyme fixed thereon, such that a mixed gas stream entering the inlet zone contacts enzyme which removes a selected gas from the mixed gas stream and passes the selected gas to the second phase zone. The invention also provides an alternative bioreactor which comprises buoyant beads coated with enzyme, floating on the surface of a condensed fluid phase, in contact with a gas phase such that the active site of the enzyme is in direct contact with the gas phase, and the beads are free to rotate in response to motion in either phase, and means for producing motion in at least one phase such that portions of the beads alternately contact the gas phase and the fluid phase, bringing a selected gas into the condensed fluid phase.
REFERENCES:
patent: 4073686 (1978-02-01), Adams
patent: 5143847 (1992-09-01), Kawase et al.
McGregor Martin L.
Redding David A.
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