Enzyme supplemented baby formula

Food or edible material: processes – compositions – and products – Dormant ferment containing product – or live microorganism...

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426 34, 426 35, 426 62, 426 63, 426801, A23C9/12

Patent

active

059026170

ABSTRACT:
A baby formula is provided having enzymes added to imitate the effect of those present in normal breast milk, aiding digestion of protein, carbohydrate (simple and complex sugars), and lipid. The enzymes are either of procaryotic or eucaryotic origin, isolated from fermentation broth or tissue, or expressed from recombinant gene sequences. The enzymes are provided in a form for addition to the formula prior to feeding the infant or at the time of feeding. In the preferred form, the enzymes are provided in a form that is stable to storage in the formula, but active when the formula reaches the portion of the gastrointestinal tract where the formula would normally be digested. In the most preferred embodiment, the enzymes are provided in a matrix with an enteric coating that releases the enzyme in the upper portion of the intestine. Depending on the formulation, proteases, carbohydrate degrading enzymes such as alpha-amylase, lactase, fructase, and sucrase, or lipases, are added to the formulation.

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Textbook of Gastroenterology and Nutrition in Infancy Second Edition, edited by F. Lebenthal (Rayen press, NY 1989), Chapter 12, pp. 97, 106-109 1989); Chapter 13, pp. 121-129; Chapter 17, pp. 158-159; Chapter 24, pp. 302-303; Chapter 26, pp. 332-332; Chapter 35, pp. 436-437.
Alemi, et al., "Fat Digestion in Very Low-Birth-Weight Infants: Effect of Addition of Human Milk to Low-Birth-Weight Formula", Pediatrics vol. 68, No. 4, pp. 484-489 (Oct. 4, 1981).
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Textbook excerpt provided by Dr. Edith Pilzer, Pediatric Gastroenterologist for applicant's child, No date.

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