Enzyme stabilization with poly-L-lysine

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

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435183, 435193, 435195, 435209, 435233, 530300, 530324, 530332, A61L 3800, C12N 496

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active

056747268

ABSTRACT:
An enzyme reaction stabilizer consisting of poly-L-lysine or its salt as an effective constituent, a method for using the enzyme reaction stabilizer, and an enzyme preservative consisting of poly-L-lysine or its salt as an effective constituent are disclosed in this invention. While enzyme reactions are carried out, the enzyme reaction stabilizer and the method for using it prevents both the deactivation of enzymes due to the proliferation of included microorganisms and the decomposition of the reaction products and there is an advantage in that the enzyme reaction stabilizer can easily be separated from the reaction products. On the other hand, while the enzyme solution is preserved, the enzyme preservative of this invention prevents the deactivation of the enzyme due to the proliferation of included microorganisms in the enzyme solution or the enzyme preserving solution. Even though the enzyme solution or the enzyme preserving solution may be supplied to the enzyme reactions, the enzyme reactions are not inhibited at all. The enzyme preservative of the present invention can easily be separated and removed from the reaction products.

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