Enzyme preparations stabilized with inorganic salts

Details Enzyme preparations stabilized with inorganic salts Enzyme preparations stabilized with inorganic salts

1996-07-29

1998-10-27

Naff, David M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435 41, 435183, 435200, 426623, C12N 996, C12N 924, C12N 900

Patent

active

058277099

ABSTRACT:
The present invention discloses methods to improve the processing and storage stability of dry enzyme preparations. To this extent an inorganic salt, e.g. MgSO.sub.4, is dissolved in an enzyme containing solution which is subsequently dried, using e.g. spray drying. Not only does the addition of salt improve the yield of enzyme activity upon drying, also the storage and processing stability of the obtained solid composition containing the enzyme and the inorganic salt are improved with respect to enzyme activity. The invention further discloses solid compositions comprising enzymes and inorganic salts. Preferably the enzymes comprise phytase, protease, hemicellulase, cellulase, and mixtures thereof, and the inorganic salts are divalent cations comprising zinc, magnesium, or calcium. The concentration of the inorganic salt is at least 5%, preferably at least 15%, more preferably at least 30%, still more preferably at least 60%, and most preferably at least 90% (w/w).

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