Enzyme-polyelectrolyte coacervate complex and method of use

Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;...

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C12N 1104

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active

058342710

ABSTRACT:
Described are unique preferred enzyme coacervate compositions and their use in catalyzing the reaction of substrates to which the enzyme is specific. Preferred coacervates of the invention are complex coacervates formed by complexing enzymes with polyelectrolytes.

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Patrickios et al. (1994) ACS Symposium Series, 548, "Interaction of Proteins with Acrylic Polyampholytes", pp. 257-267.
Liebl et al. (1975) "Polymerizations and Similar Reactions of ADP Catalyzed by Polynucleotide Plosphorylase of Proteinoids in Microsystems", in Proceed. IUB Symp. Prot. Struct. Evol., Ed., Fox et al., Dekker, New York, pp. 223-232.
Park et al. (1992) Macromolecules, 25(1), "Effects of Protein Charge Heterogeneity in Protein-Polyelectrolyte Complexation", pp. 290-295.
Xia et al. (1993) J. Phys. Chem., 97(17), "Electrophoretic and Quasi-Elastic Light Scattering of Soluble Protein-Polyelectrolyte Complexes", pp. 4528-4534.

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