Enzyme inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S396000, C514S397000, C514S399000

Reexamination Certificate

active

07728146

ABSTRACT:
There is disclosed herein compounds of formula (I),wherein:R1, R2, R3, R4and R5are defined throughout the description and the claims. The compounds of formula (I) are useful for the treatment of neurological diseases and neurodegenerative diseases, e.g. anxiety, depression, Alzheimer's disease etc.

REFERENCES:
patent: 6011155 (2000-01-01), Villhauer
patent: 6107317 (2000-08-01), Villhauer
patent: 6110949 (2000-08-01), Villhauer
patent: 6124305 (2000-09-01), Villhauer
patent: 196164866 (1997-10-01), None
patent: 19828113 (2000-01-01), None
patent: 19828114 (2000-01-01), None
patent: 19834591 (2000-02-01), None
patent: 477778 (1992-04-01), None
patent: 1258476 (2002-11-01), None
patent: 9515309 (1995-06-01), None
patent: 9640143 (1996-12-01), None
patent: 9740832 (1997-11-01), None
patent: 9819998 (1998-05-01), None
patent: 9938501 (1999-08-01), None
patent: 9946272 (1999-09-01), None
patent: 9961431 (1999-12-01), None
patent: 9967228 (1999-12-01), None
patent: 9967229 (1999-12-01), None
patent: 0007617 (2000-02-01), None
patent: 0119866 (2001-03-01), None
patent: 0134594 (2001-05-01), None
patent: 0140180 (2001-06-01), None
patent: 0155105 (2001-08-01), None
patent: 0168603 (2001-09-01), None
patent: 0181304 (2001-11-01), None
patent: 0181337 (2001-11-01), None
patent: 0202560 (2002-01-01), None
patent: 0204610 (2002-01-01), None
patent: 0231134 (2002-04-01), None
patent: 0234242 (2002-05-01), None
patent: 0234900 (2002-05-01), None
patent: 0238541 (2002-05-01), None
patent: 02083128 (2002-10-01), None
patent: 03000180 (2003-01-01), None
patent: 03000181 (2003-01-01), None
patent: 03000250 (2003-01-01), None
patent: 03002530 (2003-01-01), None
patent: 03002531 (2003-01-01), None
patent: 03002553 (2003-01-01), None
patent: 03002593 (2003-01-01), None
patent: 03004496 (2003-01-01), None
patent: 03024942 (2003-03-01), None
patent: 03024965 (2003-03-01), None
patent: 03033524 (2003-04-01), None
patent: 03035057 (2003-05-01), None
patent: 03035067 (2003-05-01), None
patent: 03037327 (2003-05-01), None
patent: 03040174 (2003-05-01), None
patent: 03045977 (2003-06-01), None
patent: 03055881 (2003-07-01), None
patent: 03057144 (2003-07-01), None
patent: 2004004498 (2004-01-01), None
patent: 2004026822 (2004-01-01), None
patent: 2004018460 (2004-03-01), None
patent: 2004033455 (2004-04-01), None
patent: 2004037169 (2004-05-01), None
patent: 2004043940 (2004-05-01), None
patent: 2004050022 (2004-06-01), None
patent: 2004052850 (2004-06-01), None
patent: 2004058266 (2004-07-01), None
patent: 2004064778 (2004-08-01), None
patent: 2004069162 (2004-08-01), None
patent: 2004071454 (2004-08-01), None
patent: 2004076433 (2004-09-01), None
patent: 2004076434 (2004-09-01), None
patent: 2004048352 (2004-10-01), None
patent: 2004087053 (2004-10-01), None
patent: 2004089362 (2004-10-01), None
patent: 2004098591 (2004-11-01), None
patent: 2004099185 (2004-11-01), None
patent: 2004103276 (2004-12-01), None
patent: 2004103993 (2004-12-01), None
patent: 2004108730 (2004-12-01), None
patent: 2004110436 (2004-12-01), None
patent: 2004111041 (2004-12-01), None
patent: 2004112701 (2004-12-01), None
patent: 2005000846 (2005-01-01), None
patent: 2005000848 (2005-01-01), None
patent: 2005011581 (2005-02-01), None
patent: 2005016911 (2005-02-01), None
patent: 2005023762 (2005-03-01), None
patent: 2005025554 (2005-03-01), None
patent: 2005026148 (2005-03-01), None
patent: 2005030751 (2005-04-01), None
patent: 2005037828 (2005-04-01), None
patent: 2005040095 (2005-05-01), None
patent: 2005044195 (2005-05-01), None
patent: 2005047297 (2005-05-01), None
patent: 2005051950 (2005-06-01), None
patent: 2005056003 (2005-06-01), None
patent: 2005056013 (2005-06-01), None
patent: 2005058849 (2005-06-01), None
patent: 2005075426 (2005-08-01), None
patent: 2005079795 (2005-09-01), None
patent: 2005082348 (2005-09-01), None
patent: 2005085246 (2005-09-01), None
patent: 2005087235 (2005-09-01), None
patent: 2005095339 (2005-10-01), None
patent: 2005095343 (2005-10-01), None
patent: 2005095381 (2005-10-01), None
patent: 2005108382 (2005-11-01), None
patent: 2005113510 (2005-12-01), None
patent: 2005116014 (2005-12-01), None
patent: 2005116029 (2005-12-01), None
patent: 2005118555 (2005-12-01), None
patent: 2005120494 (2005-12-01), None
patent: 2005121089 (2005-12-01), None
patent: 2005121131 (2005-12-01), None
patent: 2005123685 (2005-12-01), None
Souillac, et al., Characterization of Delivery Systems, Differential Scanning Calorimetry in Encyclopedia of Controlled Drug Delivery, 1999, John Wiley & Sons, pp. 212-227.
Vippagunta et al., Advanced Drug Delivery Reviews, 48 (2001), pp. 3-26.
Golub et al., Science, vol. 286, Oct. 15, 1999, pp. 531-537.
Xu, Jinyou et al, Discovery of potent, selective, and orally bioavailable pyridone-based dipetidyl peptidase-4 inhibitors, Bioogranic & Medicinal Chemistry Letters 2006 vol. 16 pp. 1346-1349.
Pederson, Raymond A. et al., Improved glucose tolerance in Zucker fatty rats by oral adminsitration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide, Diabetes 1998 vol. 47 pp. 1253-1258.
Lankas, George R. et al, Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes, Diabetes 2005 vol. 54 pp. 2988-2994.
Pauly, Robert P. et al, Improved glucose tolerance in rats treated with dipeptidyl peptidase IV (CD26) inhibitor Ile-thiazolidide, Metabolism 1999 vol. 48 pp. 385-389.
Bundgaard, Hans, Design of prodrugs, Elsevier 1985.
Sedo, Aleski et al., Dipeptidyl peptidase IV-like molecules: homologous proteins or homologous activities?, Biochimica et Biophysica Acta 2001 vol. 1550 pp. 107-116.

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