Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reissue Patent
2007-04-17
2007-04-17
Barts, Samuel (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C514S550000, C560S150000, C562S556000
Reissue Patent
active
10407204
ABSTRACT:
A compound of formula (I)whereinR1is a C1-6straight or branched chain alkyl group, a C2-6alkenyl group, a C2-6alkynyl group, a C3-6cycloalkyl group or a C3-6cycloalkylC1-6alkyl group, each optionally substituted by one to three groups independently selected from: —CN; —NO2; a group —COR2wherein R2is hydrogen, C1-6alkyl, —OR3wherein R3is hydrogen or C1-6alkyl or NR4R5wherein R4and R5are independently selected from hydrogen or C1-6alkyl; a group —S(O)mR6wherein m is 0, 1 or 2, R6is hydrogen, C1-6alkyl, hydroxy or NR7R8wherein R7and R8are independently hydrogen or C1-6alkyl; a group PO(OR9)2wherein R9is hydrogen or C1-6alkyl; a group NR10R11wherein R10and R11are independently selected from hydrogen, C1-6alkyl, —COR12wherein R12is hydrogen or C1-6alkyl, or —S(O)m′R13wherein m′ is 0, 1 or 2 and R13is hydrogen or C1-6alkyl; halo; or a group —OR14wherein R14is hydrogen, C1-6alkyl optionally substituted by one to three halo atoms, C6-10aryl or —COR15wherein R15is hydrogen or C1-6alkyl; p is 2 or 3, q is 1 or 2 and n is 0 or 1 and all salts, esters, amides and physiologically acceptable prodrugs thereof; pharmaceutical uses and formulations therefor; and processes for their preparation are disclosed.
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Clark Helen Alice Rebecca
Davies Patricia Ifeyinwa
Drysdale Martin James
Franzmann Karl Witold
Hodson Harold Francis
Barts Samuel
Nixon & Vanderhye P.C.
Smithkline Beecham Corporation
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