Enzyme inhibitor acaricides I

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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A01N 3752

Patent

active

057959170

ABSTRACT:
The invention provides novel methods of controlling mite infestations of plants. The novel methods employ the step of applying an effective amount of a compound that can inhibit the proteolytic activity of trypsin and trypsin-like proteinase. Preferred compounds for use in the subject methods are Pefabloc SC, pentamidine, soybean trypsin inhibitor, lima bean trypsin inhibitor, and aprotinin.
Another aspect of the invention is to provide formulations for use in applying to plants so as to control mites. The formulations comprise one or more inert carrier and a compound that can inhibit the proteolytic activity of trypsin. Preferred acaricidal compounds for use inclusion in the subject formulations are Pefabloc SC, pentamidine, soybean trypsin inhibitor, lima bean trypsin inhibitor, and aprotinin. Another aspect of the invention is to provide improved methods for the screening of compounds that have acaricidal activity. The screening method of the invention limits the range of compounds for screening to those compounds capable of inhibiting the proteolytic activity of trypsin and trypsin-like proteinases.

REFERENCES:
The Merck Index, 11th Ed. (1989) p. 718 #4475.

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