Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1995-05-22
1997-03-04
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435227, C12N 980, C12N 978
Patent
active
056078501
ABSTRACT:
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides said phthalyl amidase, means for producing it by culturing the natural organism from which the activity was identified, and methods for using said phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides.
REFERENCES:
Yang et al. J. Biol. Chem. 268:10870, 1993.
Kukolja et al. Croatica Chemica Acta 49:779, 1977.
Toyoura et al. Chem. Pharm. Bull. 7:789, 1959.
Briggs Barbara S.
Zmijewski, Jr. Milton J.
Blalock Donna K.
Cantrell Paul R.
Eli Lilly and Company
Hendricks Keith D.
Patterson Jr. Charles L.
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