Enzyme from microbial source: phthalyl amidase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435227, C12N 978, C12N 980

Patent

active

054459591

ABSTRACT:
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides said phthalyl amidase, means for producing it by culturing the natural organism from which the activity was identified, and methods for using said phthalyl amidase to remove the phthalyl moiety from phthalyl-containing amides.

REFERENCES:
Yang et al., J. Biol. Chem. 268:10870, 1993.
Kukolja et al., Croatica Chemica Acta 49:779, 1977.
Toyoura et al., Chem. Pharm. Bull. 7:789, 1959.

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