Enzyme conjugates and method of preparation and use

Details Enzyme conjugates and method of preparation and use Enzyme conjugates and method of preparation and use

1978-03-24

1980-08-19

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435 7, 260112R, 260112B, 424 12, C12N 996, G01N 3354

Patent

active

042185394

ABSTRACT:
Novel enzyme conjugates useful in immunoassay methods are prepared with the use of a novel coupling reagent of N-succinimidyl (4-iodoacetyl) aminobenzoate by reacting the coupling reagent, firstly, with an amino-containing macromolecule, and, thereafter, with a sulfhydryl-containing enzyme, the enzyme conjugate prepared in a high yield and of high specificity.

REFERENCES:
patent: 4144131 (1979-03-01), Richardson

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