Enzyme composition adapted for application to ruminant feed...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Specially adapted for ruminant animal

Reexamination Certificate

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C424S442000, C424S094100, C424S094200, C424S094610, C426S053000, C435S267000, C435S274000, C435S275000, C435S276000, C435S277000

Reexamination Certificate

active

06623750

ABSTRACT:

FIELD OF THE INVENTION
The present invention relates to ruminant feed conditioners and modifiers and application techniques relating thereto. More particularly, the present invention relates to exogenous enzyme compositions adapted for treating ruminant feed to improve protein digestability and retention and decrease nitrogen-containing waste.
BACKGROUND OF THE INVENTION
As described in more detail in U.S. Pat. No. 5,662,901, the practice of applying products containing active enzymes to ruminants feed is known. In particular, such enzymes can be utilized to increase the food value of grains and feeds such as corn, grain sorghum, barley, rye and oats. Application of certain active enzymes to ruminant feed has been shown to increase carbohydrate availability and fiber digestability, which contribute to increased rate of weight gain and feed utilization efficiency.
Despite these improvements in feed utilization, pollution from nitrogen-containing waste, including waste containing nitrates and ammonia, continues to be an environmental problem associated in particular with cattle feedlots and dairy operations. Clearly, if one were able to cause ruminants to increase retention of the nitrogen content of feed, a concomitant decrease in nitrate and other nitrogen-containing waste would be expected to occur. Techniques for this purpose include hormonal supplements for ruminants, but such techniques are increasingly disfavored, in part due to the other possible health effects on individuals consuming meat products from the ruminants.
It can thus be seen that a need remains for a safe and economical technique which decreases production of nitrogen-containing wastes from ruminants. There also remains a need for techniques and compositions which increases protein content of milk from dairy cows and protein content of meat in cattle. It is therefore against the background described above that the advances of the present invention have been made.
SUMMARY OF THE INVENTION
The present invention relates to enzyme feed supplements containing fungal cellulase produced by
Trichoderma viride
which are specially adapted for increasing protein digestability of feed by dairy cow, cattle and other ruminants. Preferred embodiments of the present invention include enzyme formulations adapted for application to easier to digest grains such as corn, and enzyme formulations adapted for application to harder to digest grains, such as grain sorghum, to which are added
Trichoderma viride
cellulase enzyme. An increase in protein digestability has been evidenced by increased protein content of milk and increased nitrogen retention from the feed.


REFERENCES:
patent: 5662901 (1997-09-01), Tobey, Jr. et al.
patent: 5720971 (1998-02-01), Beauchemin et al.
“1999 Official Publication Association of American Feed Control Officials Incorporated”, by Association of American Feed Control Officials, Copyright © 1999, pp. 207-217.
“Multicel 185”, George A. Jeffreys and Company, Inc., published on or before Jan. 1, 2000.
“Material Safety Data—Multicel 185”, Nugen, Inc., Mar. 1, 1994, pp. 1-4.
“Spezyme® CP”, Genencor® Cellulase Enzyme, on or before Jan. 1, 2000.
“Effect of Cell Wall Degrading Enzyme Preparations on the In-Vitro N Solubility of Feedstuffs”, J.W. Cone, A.H. Van Gelder and J. Van Der Meulen, Received Sep. 8, 1994, pp. 242-246, 248, 250 and 252.
Food Carbohydrates, Edited by David R. Lineback, Ph.D., Raleigh, North Carolina and George E. Inglett, Ph.D., Peoria, Illinois, AVI Publishing Company, Inc., Westport, Connecticut, “Analysis of Polysaccharides”, pp. 356-360.
“Joint Proceedings of the Second International Roundtable on Animal Feed Biotechnology—Probiotics and Workshop on Animal Feed Enzymes”, Edited by S.K. Ho, D.A. Leger, and E.E. Lister, Ottawa, Ontario, Canada, Feb. 3-4, 1994, “Are Enzymes Effective: Application to Monogastric Animals”, pp. 149-184.
“Nutritional implications of feeding enzyme-treated wheat bran to pigs”, by Johan Inborr, Jan Van Der Meulen and Jari Puhakka, on or before Jan. 1, 2000, pp. 3, 6 and 22.
“Probiotic Concepts: The Production and Use of Direct Fed Microbials and Enzyme Bearing Products in Animal Management”, by James F. Tobey, Jr., 1992.
Biotechnology In the Feed Industry: 1994 and Beyond, T.P. Lyons, Alltech Inc., Nicholasville, KY,® 1994, pp. 83-85.
“Upgrading recycled pulps using enzymatic treatment”, Gerhard Stork, Helena Pereira, Thomas M. Wood, Eva Maria Dusterhoft, Annette Toft, and Juergen Puls, vol. 78 No. 2 Tappi Journal 79, Feb. 1995, pp. 79, 82, 83 and 87.
“Feed Additive for Animal Use”, Kyowa Hakko Kogyo Co Ltd, Konno Toshiyasu, Matsuura Ichiro and Shirahata Kimikatsu, Aug. 3, 1993, Abstract of JP05192093A.
Influence of Sodium Hyroxide and Enzyme Additions on Nutritive Values of Rice Straw, C.M. Wilis, O. T. Stallcup and D. L. Kreider, University of Arkansas, pp. 303-308, 1980.

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