Enzyme complexes and their use

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602391, 260 25P, C07D49942

Patent

active

040012646

ABSTRACT:
Novel water-insoluble enzyme complexes are provided which comprise a penicillin acylase enzyme adsorbed on a water-insoluble polymer substrate which is a polymer or copolymer of methacrylic acid and cross-linked with a cross-linking agent selected from glutaraldehyde, glyoxal and formaldehyde. The complexes are useful in the production of 6-APA from penicillins G and V.

REFERENCES:
patent: 3705084 (1972-12-01), Reynolds
Regan et al., Biotechnology and Bioengineering, vol. XVI, pp. 333-343, (1974).

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