Enzyme complex having collagenolytic activity isolated from crab

Details Enzyme complex having collagenolytic activity isolated from crab Enzyme complex having collagenolytic activity isolated from crab

1990-06-06

1992-09-01

Naff, David M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435820, C12N 948

Patent

active

051438372

ABSTRACT:
An enzyme complex having collenagenolytic activity, comprising a mixture of collegenolytic proteases from crabs is disclosed. The proteases of the complex have the ability to cleave bovine lens capsule collagen type IV, have molecular weights from about 23,000 to 36,000 daltons, and possess a collagenolytic activity of more than about 3.300 Mandl units/mg at a pH of 7.5. The complex is isolated in aqueous solutions without the use of organic solvents from the hepatopancreas of crabs. The crabs from which the complex can be isolated are of the paralithodes and chinocetes species of crabs.

REFERENCES:
patent: 3909358 (1975-09-01), Stanley et al.
patent: 4329430 (1982-05-01), Klein et al.
Bavanowski et al, Partial characterization of a . . . J, of Food Science, vol. 49, 1984.
Welgus et al, Degradation of Collagen Substrates, Biochemistry, vol. 22, pp. 2228-2233, 1983.
Grant et al, A Collagenolytic Serine Protease . . . 22, 354-358, 1983.
Grant et al, Substrate Specificity of the Biochemistry, 19, 6089-6095, 1980.
Eisen et al, A Collagenolytic Protease . . . Biochemistry, vol. 12, No. 9, pp. 1814-1822, 1973.
Klimova et al., The Isolation and properties of . . . , BBRC, vol. 166, No. 3, pp. 1411-1420, 1990.
Grant et al., Collagenolytic Protease from Fiddler . . . , Meth. in Enzy., vol. 80, pp. 722-734, 1981.

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