Enzyme castration of animals

Details Enzyme castration of animals Enzyme castration of animals

1992-01-14

1992-11-17

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424 9465, A61K 3754

Patent

active

051641810

ABSTRACT:
Male animals may be chemically castrated by injecting both testes and/or both spermatic cords with a castratingly effective amount of a protease enzyme such as a chymopapain-rich enzyme preparation.

REFERENCES:
patent: 4156427 (1979-05-01), Fahim
patent: 4339438 (1982-07-01), Fahim
patent: 4356189 (1982-10-01), Stagg et al.
Article by Craig N. Carter, DVM, MS entitled "Pet Population Control: Another Decade Without Solutions" JA VMA, vol. 197, No. 2, Jul. 15, 1990, pp. 192-194.
Article by Donald K. Kunimitsu et al. entitled: "Chymopapain B" Methods in Enzymology, vol. XIX, Proteolytic Enzymes, edited by Gertrude E. Perlmann et al. (1970) Academic Press.
Article by Paul J. Garvin et al. entitled "Chymopapain: A Pharmacologic and Toxicologic Evaluation in Experimental Animals", Clinical Orthopaedics No. 42 (1965) J. B. Lippincott Company pp. 204-223.
Article by Ivan J. Stern, Ph.D. entitled "Biochemistry of Chymopapain", Clinical Orthopaedics and Related Research, No. 67, Nov.-Dec., 1969, pp. 42-46.
Article by Robert M. Gesler, Ph.D. entitled "Pharmacologic Properties of Chymopapain, Clinical Orthopaedics" No. 67 (1969) pp. 47-51.

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