Enzyme-bound-polyidothyronine

Details Enzyme-bound-polyidothyronine Enzyme-bound-polyidothyronine

1977-03-17

1979-10-16

Naff, David M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

424 12, 435 7, C07G 702, G01N 3114

Patent

active

041712447

ABSTRACT:
An enzyme-polyidothyronine conjugate for use in determining polyiodothyronine by immunoassay is prepared containing an enzyme which is reversibly deactivated by polyiodothyronine and is reactivated by an antibody binding to the polyiodothyronine of the conjugate. Preferred enzymes are malate dehydrogenase and triose phosphate isomerase.

REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 4040907 (1977-08-01), Ullman et al.

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