Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1987-05-29
1990-02-20
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435189, 4352521, 435822, C12P 760, C12N 902, C12R 101
Patent
active
049026178
ABSTRACT:
The present invention relates to novel enzyme having L-sorbosone dehydrogenase activity and a process for producing the same. This L-Sorbosone dehydrogenase enzyme provided by the present invention catalyzes the oxidation of L-sorbosone to 2-keto-L-gulonic acid in the presence of nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate as a coenzyme. 2-KGA is an important precursor for the production of vitamin C.
REFERENCES:
patent: 3907639 (1975-09-01), Makover et al.
Acta Microbiologica Sinica, 21(2), 185-191, (1981), (Yan et al.).
Krieg, Ed., Bergey's Manual of Systematic Bacteriology, vol. 1, pp. 275-278, 1984.
English Abstract of Yan et al., Reference R.
Sato, The Journal of Biochem., vol. 66, No. 4, p. 521, (1969).
Martin et al., European J. Appl., Microbiol. 3, 91-95, (1976).
Makover et al., Biotechnology and Bioengineering, vol. XVII, pp. 1485-1514, (1975).
Fujiwara Akiko
Hoshino Tatsuo
Sugisawa Teruhide
Epstein William H.
Gould George M.
Hoffmann-La Roche Inc.
Leon Bernard S.
Wax Robert A.
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