Enzyme and DNA coding therefor

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 681, 435219, 435232, 530350, 530855, 536 27, C12D 2100, C12H 900

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active

051963167

ABSTRACT:
The invention concerns a peptidylhydroxyglycine N-C lyase (PHL) catalyzing the reaction

REFERENCES:
patent: 4745051 (1988-05-01), Smith et al.
Young & Tamburini, Enzymatic Peptidyl .alpha.-Amidation Proceeds Through Formation of an .alpha.-Hydroxyglycine Intermediate, Mar. 1989, 1933-1934.
Stoffers et al. Proc. Natl. Acad Sci USA 86 735-739 1989.
Bradbury et al., Nature, 298:686 (1982).
Eipper et al., PNAS:USA, 80:5144 (1983).
Glembotski et al., J. Biol. Chem., 259:6385 (1984).
Murthy et al., J. Biol. Chem., 261:1815 (1986).
Eipper et al., Molec. Endocrinol., 1:777 (1987).

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