Enzymatically amplified piezoelectric specific binding assay

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...

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435 6, 435 78, 435 21, 435 28, 435173, 435817, 435 792, 435 794, 436501, 436531, 436532, 436537, 436544, 436547, 436806, 204403, C12Q 100, G01N 3353, C12N 1300

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049992848

ABSTRACT:
A quartz crystal microbalance assay in which the binding of analyte to a surface on or near a quartz crystal microbalance (QCM) is detected by a conjugate which comprises an enzyme capable of catalyzing the conversion of a substrate to a product capable of accummulating on or reacting with a surface of the QCM leading to a mass change and, hence, a change in resonant frequency.

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