Enzymatic synthesis of oligonucleotides using digestible templat

Details Enzymatic synthesis of oligonucleotides using digestible templat Enzymatic synthesis of oligonucleotides using digestible templat

1995-06-07

1999-08-03

Marschel, Ardin H.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 6, 435 912, 514 44, 536 243, 536 2433, 536 253, C12P 1934, C12Q 168, A01N 4304, C07H 2104

Patent

active

059324503

ABSTRACT:
The present invention describes methods of synthesizing oligonucleotides. In particular, it relates to methods of enzymatically synthesizing chirally pure oligonucleotides using templates which can be digested after synthesis. By using digestible templates, separation and purification of the synthesized oligonucleotides are greatly facilitated.

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