Enzymatic production of sphingophospholipid derivatives

Details Enzymatic production of sphingophospholipid derivatives Enzymatic production of sphingophospholipid derivatives

1984-04-10

1988-11-01

Hazel, Blondel

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 92, 435 68, 435 52, 435106, 435113, 435115, 435120, 435121, 435122, 435125, 435127, 435128, 435118, 435131, 435117, C12P 1930, C12P 1932, C12P 900, C12P 1700

Patent

active

047820195

ABSTRACT:
A process for producing a sphingophospholipid derivative comprising reacting a sphingophospholipid with a specified compound having an alcoholic hydroxyl group selected from the group consisting of specified primary alcohol compounds, specified secondary alcohol compounds and specified saccharides or their phenol glycosides in the presence of phospholipase DM.

REFERENCES:
Fauvel, J. et al., Studies on Glycerophospholipids, Biochim. Biophys. Acta, vol. 792, pp. 72-78, Jan. 17, 1984.
R. M. C. Dawson, "The Formation of Phosphatidylglycerol and Other Phospholipids by the Transferase Activity of Phospholipase D, J. Biochem., 102, (1967), pp. 205-210.
F. M. Davidson & C. Long "The Structure of the Naturally Occurring Phosphoglycerides, J. Biochm., vol. 69, (1958), pp. 458-466.
Y. Okawa & T. Yamaguchi, "Studies on Phospholipases from Streptomyces", J. Biochem., vol. 78, (1975) pp. 363-372.
S. F. Yang, et al., "Transphosphatidylation by Phospholipase D, J. Biochem., vol. 242, (1967), pp. 477-484.

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