Enzymatic process for the manufacture of ascorbic acid 2-keto-L-

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435195, 435197, 435219, 4352523, 435836, 435847, 435913, 435921, 435933, 536 232, C12P 758, C12N 914, C12N 120, C12N 100

Patent

active

058174907

ABSTRACT:
The present invention is directed toward efficient, high-yield processes for making ascorbic acid, 2-keto-L-gulonic acid, and esters of 2-keto-L-gulonic acid. The processes comprise reacting the appropriate starting materials with a hydrolase enzyme catalyst such as a protease, an esterase, a lipase or an amidase.

REFERENCES:
patent: 2301811 (1942-11-01), Reichstein
patent: 5008193 (1991-04-01), Anderson et al.
patent: 5441882 (1995-08-01), Estell et al.
D. G. Hayes, "The Catalytic Activity of Lipases Toward Hydroxy Fatty Acids-A Review", Journal of the American Oil Chemists' Society, vol. 73, No. 5, pp. 543-549, May 1, 1996.
T. Reichstein et al., Helv. Chim. Acta, vol. 17, pp. 311-328 (1934).
T. Sonoyama et al., Applied and Envtl. Microbiology, vol. 43, pp. 1064-1069 (1982).
M. Shinjoh et al., Applied and Envtl. Microbiology, vol. 61 pp. 413-420 (1995).
S. Anderson et al., Science, vol. 230, pp. 144-149 (1985).
Yamazaki, J. Agri. Chem. Soc. Japan, vol. 28, pp. 890-894 (1954) (translation not included).
Chemical Abstracts, vol. 50, 5992d.
F. Thiel, Catalysis Today, pp. 517-536 (1994).
A. L. Gutman et al., Tetrahedron Lett., vol. 28, pp.3861-3864 (1987).
A. L. Gutman et al., Tetrahedron Lett., vol. 28, pp. 5367-5368 (1987).
Enzyme Nomenclature (Academic Press, 1992) (cover pages only).
E. L. Smith et al., J. Biol. Chem., vol. 243, pp. 2184-2191 (1968).
M. Matsushima et al., FEBS Lett., vol. 293, pp. 37-41 (1991).
J. Uppenberg et al., Structure, vol. 2, pp. 293-308, 453 (1994).
H. J. Duggleby et al., Nature, vol. 373, pp. 264-268 (1995).
Molecular Cloning -A Laboratory Manual, Cold Spring Harbor Laboratory Press, NY.Y. (1989), vol. 1, 2, and 3 (title pages and tables of contents only).
Current Protocols in Molecular Biology, F. M. Ausubel et al., editors, Greene Publishing Associates and Wiley-Interscience, N.Y. (1989) (title pages and table of contents only).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Enzymatic process for the manufacture of ascorbic acid 2-keto-L- does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enzymatic process for the manufacture of ascorbic acid 2-keto-L-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enzymatic process for the manufacture of ascorbic acid 2-keto-L- will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-75999

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.