Enzymatic process for producing a galactosyl.beta.1,3glycal disa

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435207, C12P 1912, C12N 938

Patent

active

054037263

ABSTRACT:
An enzymatic process is disclosed for the preparation of galactosyl.beta.1,3glycal disaccharides such as Gal.beta.1,3Glucal, an intermediate useful in Le.sup.a preparation and an inhibitor of .beta.-galactosidase. The process utilizes .beta.-galactosidase, an enzyme usually used for bond breaking, to form a bond between a galactoside and a glucal such as glycal, a 6-O--C.sub.1 -C.sub.6 acylglucal or 6-O--C.sub.1 -C.sub.6 acetylgalactal.

REFERENCES:
patent: 4918009 (1990-04-01), Nilsson
patent: 5180674 (1993-01-01), Roth
patent: 5246840 (1993-09-01), Nilsson
Distler et al., Complex Carbohydrates, Edited by Victor Ginsburg, Methods in Enzymology, pp. 514-520, 1978.
Leppanen et al., Biochemistry, 1991, 30, 9287-9296.
Petit et al., Tetrahedron Letters, vol. 32, No. 43, 6125-6128, 1991.
Cummings et al., J. of Biol. Chem., vol. 259, No. 10, 6253-6260, 1984.
Presant et al., J. of Biol. Chem., vol. 247, No. 21, 6937-45, 1972.
Distler et al., J. of Biol. Chem., vol. 248, No. 19, 6772-6780, 1973.
Vandenheede et al., J. of Biol. Chem., vol. 247, No. 24, 7885-7889, 1972.
Sheares et al., J. of Biol. Chem., vol. 257, No. 2, 599-602, 1982.
Toone et al., Tetrahedron, 45(17), 5365-5422, 1989.
Lehmann et al., Carbohydrate Research, 58(1977), 73-78.
Nilsson, Tibtech, 1988, vol. 6, pp. 256-264.
Lehmann et al., Carbohydrate Research, 23(1972), 359-368.
Lehmann et al., Carbohydrate Research, 58(1977), 65-72.
Legler, Advances in Carbohydrate Chemistry and Biochemistry, vol. 48, pp. 319-384, 1990.
Sinnott, Chem. Rev., 1990, 90, 1171-4202.
Kaila et al., J. Org. Chem., 1992, 57, 4576-4578.
Dettinger et al., Carbohydrate Research, 74(1979), 301-307.
Dean et al., J. of Biol. Chem., vol. 254, No. 20, pp. 10006-10010, 1979.
Sandermann, Jr., Eur. J. Biochem., 80, 507-515, 1977.
Karz et al., Carbohydrate Research, 93(1981), C14-C20.
Nilsson, Carbohydrate Research, 167, 1987, pp. 95-103.
Nilsson, Ann. N. Y. Acad. Sci., 542 (Enzyme Eng. 9), 1988, 383-9.
Nilsson, Carbohyd. Res., 188:9-17 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Enzymatic process for producing a galactosyl.beta.1,3glycal disa does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enzymatic process for producing a galactosyl.beta.1,3glycal disa, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enzymatic process for producing a galactosyl.beta.1,3glycal disa will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2380065

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.