Enzymatic process for preparing glucuronides

Details Enzymatic process for preparing glucuronides Enzymatic process for preparing glucuronides

1984-01-31

1986-05-13

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435280, C12P 1958, C07P 4100

Patent

active

045886865

ABSTRACT:
An in vitro enzymatic process which efficiently converts (+,-)-tropicamide to essentially pure (+), (-)-tropicamide O-.beta.-D-glucuronide. This product is then separated, advantageously, into the novel compounds (+)-tropicamide O-.beta.-D-glucuronide and (-)-tropicamide O-.beta.-D-glucuronide. The products disclosed herein absorb ultraviolet light, and, thus, can be incorporated into suitable plastic films which are then useful for screening out harmful ultraviolet radiation for the protection of packaged goods. Also, the products can be used to protect the skin against burning by sunlight.

REFERENCES:
patent: 4478936 (1984-10-01), Herlihy et al.
Ando et al., J. Antibiotics, 23, 408-413 (1970).
Johnson et al., Prep. Biochem., 9, 391-406 (1979).

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