Enzymatic process for enantiomer-specific perparation of mercapt

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435107, 435117, 435121, 435130, 435170, 435171, 435180, 435196, 435197, 435822, 435874, 435877, 435911, 435917, C12P 1300, C12P 1710, C12P 1100, C12R 100

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051067366

ABSTRACT:
An enzymatic process for the enantiomer-specific preparation of mercapto alkanoic acids by stereoselective hydrolysis of mercapto or thioester alkanoic acid esters.

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Wang, Y. F. et al., Tetrahedron Letters, vol. 25, No. 44, pp. 4999-5002 (1984) "Bifunctional chiral synthons via biochemical methods 4 chiral precursors to (+)-biotin and (-)-A-factor."
Tombo, G. M. R. et al., Tetrahedron Letters, vol. 27, No. 47, pp. 5707-5710 (1986) "Synthesis of both enantiomeric forms of 2-substituted 1,3-propanediol monoacetates starting from a common prochiral precursor, using enzymatic transformations in aqueous and in organic media."

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