Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...
Patent
1995-05-03
1996-06-04
Marx, Irene
Chemistry: molecular biology and microbiology
Process of utilizing an enzyme or micro-organism to destroy...
Resolution of optical isomers or purification of organic...
435875, C12P 4100
Patent
active
055232337
ABSTRACT:
The present invention relates to a process for converting a racemic mixture of 3,3-diethyl-4-[(4-carboxy)phenoxy]-2-azetidinone esters into the corresponding (S)-acid using lipase derived from Pseudomonas sp. The process provides the target acid in high enantiomeric excess.
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C. Marcin, et al, Journal of Industrial Microbiology, 12 (1993) 29-34 (1993) 29-34 (1993) 29-34.
L. Katz, et al, Journal of Industrial Microbiology, 11 (1993) 89-94.
M. Chartrain, et al, Enzyme Microb. Technol., 15 (1993) 575-580.
M. Chartrain, et al, Journal of Fermentation and Bioengineering, vol. 76, No. 6, 487-492 1993.
K. E. Goklen, et al, Bioprocess Engineering 11 (1994) 49-56.
Chartrain Michel M.
Cvetovich Raymond
Roberge Christopher
Marx Irene
Merck & Co. , Inc.
Rose David L.
Saucier S.
Yang Mollie M.
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