Enzymatic dentifrices

Details Enzymatic dentifrices Enzymatic dentifrices

1978-01-19

1979-04-17

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ferment containing

424 48, A61K 728

Patent

active

041501136

ABSTRACT:
A novel enzymatic dentifrice comprises as its essential active ingredient an amount of glucose oxidane enzyme which forms hydrogen peroxide by oxidative decomposition of a glucose substrate provided by glucose present in saliva and tooth plaque so as to cause a substantial shift toward neutral values in the pH at the surface of teeth, when said pH is below the neutral range.

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C.A. 32, #721(2)(1938), 44 #6573i(1950).
Fitzgerald et al., Antibiotics & Chemotherapy 3(3):231-240, Mar. 1953, The In Vitro Effects of Antibiotics and Other Inhibitory Agents on Representive Oral Lactobacillii.
Volker et al., Antibiotics & Chemotherapy 6:56-62(1956), The Influence of Certain Protein Adsorbed Agents on Hamster Caries.
Welch et al., Antibiotics & Chemotherapy 2:249-254(1952), The Effect of Prolonged Use of Penicillin Toothpowder.

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