Enzymatic dentifrices

Details Enzymatic dentifrices Enzymatic dentifrices

1978-11-09

1979-12-11

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Chewing gum type

424 50, 424 94, 426 3, A61K 968, A61K 728

Patent

active

041783620

ABSTRACT:
A novel enzymatic dentifrice comprises as its essential active ingredient an amount of glucose oxidane enzyme which forms hydrogen peroxide by oxidative decomposition of a glucose substrate provided by glucose present in saliva and tooth plaque so as to cause a substantial shift toward neutral values in the pH at the surface of teeth, when said pH is below the neutral range.

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Chem. Abstracts 32:721(2), 37:1467(4); 2036(8); 3789(3); 4421(1); 38:137(6); 39:5261(1); 40:6546(6); 41:2165(c) 42:4366(a), 4625(d), 43:3857(i) 44:4055, 6573(i).
Welch et al., Antibiotics & Chemotherapy II(5) May 1952, pp. 249-254, The Effect of Prolonged Use of Penicillin Tooth Powder on the Penicillin Resistance of Oral Micro Organisms.
Fitzgerald et al., Antibiotics and Chemotherapy III(3):231-240 Mar. 1953, The In Vitro Effects of Antibiotics and Other Inhibitory Agents on Representative Oral Lactobacilli.
Volker et al., Antibiotics and Chemotherapy 6:56-62 (1956) The Influence of Certain Protein Adsorbed Agents on Hamster Caries.

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