Enucleated granulocytes, their preparation and use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 34, 435 29, 435810, 435 4, 436518, G01N 3353

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046236201

ABSTRACT:
Granulocytes, particularly neutrophilic granulocytes, also called polymorphonuclear leukocytes (PMN), have been found to retain their immunological properties after enucleation. Moreover, in contrast with normal granulocytes, enucleated granulocytes are stable when stored in frozen condition. The invention relates to the enucleated granulocytes, especially in frozen condition, to a process for preparing the enucleated granulocytes, to a process for assaying antibodies against granulocytes, and to a kit for carrying out the latter process.

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