Plastic and nonmetallic article shaping or treating: processes – Encapsulating normally liquid material – Liquid encapsulation utilizing an emulsion or dispersion to...
Patent
1993-03-29
1994-07-19
Lovering, Richard D.
Plastic and nonmetallic article shaping or treating: processes
Encapsulating normally liquid material
Liquid encapsulation utilizing an emulsion or dispersion to...
264 46, 424450, 436829, A61K 9127, A61K 9133
Patent
active
053306899
ABSTRACT:
Methods and compositions are described for the preparation of alpha-tocopherol vesicles, the bilayers of which comprise a salt form of an organic acid derivative of alpha-tocopherol such as the Tris salt form of alpha-tocopherol hemisuccinate. The method is rapid and efficient and does not require the use of organic solvents. The alpha-tocopherol vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility, thus enabling administration in vivo.
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Bergamini Michael V. W.
Bolcsak Lois E.
Janoff Andrew S.
Suddith Robert L.
Tremblay Paul A.
Bloom Allen
Feeney Joanne Longo
Lovering Richard D.
The Liposome Company Inc.
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